Stefan Terblanche will captain the Sharks from the outside centre position in their opening game against Griquas on Saturday.
Coach John Plumtree has also introduced three new faces to his Currie Cup side with Louis Ludik making his first appearance and Pat Lambie making his domestic debut. Former Perpignan flyhalf Steve Meyer is also down to start.
Plumtree has also included youngsters Kyle Cooper, Eugene van Staden and Anton Bresler on the bench.
Sharks – 15 Patrick Lambie, 14 Louis Ludik, 13 Stefan Terblanche (c), 12 Riaan Swanepoel, 11 Lwazi Mvovo, 10 Steve Meyer, 9 Rory Kockott, 8 Keegan Daniel, 7 Michael Rhodes, 6 Jacques Botes, 5 Alistair Hargreaves, 4 Steven Sykes, 3 Wiehahn Herbst, 2 Craig Burden, 1 Patric Cilliers.
Subs: 16 Kyle Cooper, 17 Eugene van Staden, 18 Anton Bresler, 19 Skholiwe Ndlovu, 20 Charl McLeod, 21 Monty Dumond, 22 Andries Strauss.