The Golden Lions have suffered three new injuries after their 38-23 win over the Free State Cheetahs last Saturday.
The major loss is lock Hendrik Roodt, who recently recovered from injury. Roodt is expected to be out for the season as he suffered a shoulder dislocation.
Flank Willie Britz and wing Deon Helberg are also out of action with wrist and ankle injuries respectively.
The Lions are already without scrumhalf Whestley Moolman (arm) and lock Stephan Greeff (leg) for the rest of the season. Flank Derick Minnie (knee), flyhalf Guy Cronje (hamstring) and centre Waylon Murray (knee) are recovering and are set to make their returns over the next two to three weeks.
There is some good news for the Lions as flank Jaco Kriel and prop CJ van der Linde rejoined the squad at training on Monday.