Clermont won an early top-of-the-table clash with Stade Francais, while there were also Top 14 victories for Racing 92, Toulouse and Lyon.
The Springboks look to bounce back after they suffered an away loss to the Pumas. They meet the Wallabies in a must win match in Brisbane.
Pro14 champions Leinster were defeated by last season's runners-up Scarlets in a tense clash on Saturday.
South Africa's Rassie Erasmus was frustrated with the way they allowed Australia to score tries while struggling on Saturday.
Danny Cipriani inspired Gloucester's comeback as a former Bath player denied the hosts victory at the Rec on Saturday.
Despite the late withdrawals of Adam Coleman and Israel Folau, Australia secured a hard-fought 23-18 victory over South Africa.
Argentina were beaten by New Zealand in Nelson but Agustin Creevy was encouraged by a competitive performance.
New Zealand's battling victory against Argentina has come at the cost of injuries to Ngani Laumape and Brodie Retallick.
Michael Cheika gained some much-needed respite as he watched his Australia side beat South Africa 23-18 in the Rugby Championship.
Though New Zealand ran out 46-24 winners over Argentina, the All Blacks' victory was far from a convincing one.