Harlequins won an entertaining encounter with Exeter Chiefs to hand them their first defeat of the Premiership season.
Three tries in eight minutes from Keith Earls helped Munster to an easy win over Edinburgh, while Ospreys nilled Zebre.
Andy Farrell will replace Joe Schmidt as Ireland head coach after the Rugby World Cup and Brian O'Driscoll has backed the call.
South Africa and London Irish tweeted their best wishes to Naka Drotske, who was shot during a robbery in Pretoria.