Owen Franks is looking forward to a new adventure in the Premiership after agreeing to join Northampton Saints.
Ellis Genge was removed from training on Thursday, but Steve Borthwick does not think there will be any 'major consequences' for the prop.
Having lost Ryan Wilson for the rest of the Six Nations earlier this week, Scotland may also have to cope without Huw Jones.
There were concerns that Iain Henderson would not feature in the Six Nations, but the lock looks set to play a part for Ireland.
Despite missing the playoffs for the first time in six seasons last year, Brumbies have handed Dan McKellar an extension.