Both Edinburgh and Glasgow Warriors are through to the European Champions Cup quarter-finals due to the former's 19-10 win over Montpellier.
Billy Vunipola will take more motivation from England's response to the 2015 Rugby World Cup than from the disappointment.
Cheetahs secured a dramatic 24-17 victory over South African rivals Southern Kings after Luan de Bruin touched down in the 85th minute.
Jack Nowell's versatility could be put to the test after Eddie Jones revealed the 25-year-old may feature for England in the pack.
Owen Farrell can thrive as captain in the absence of Dylan Hartley as England begin their Six Nations campaign against Ireland.
Owen Farrell will be England's sole captain against Ireland, with Dylan Hartley unavailable for the start of the Six Nations due to injury.
Ireland have named Johnny Sexton in their squad for the opening two Six Nations fixtures as the fly-half recovers from a knee injury.
With selection for the Six Nations looming, full-back Mike Brown says his burning desire to play for England is as strong as ever.
Malakai Fekitoa has given Wasps a huge lift by agreeing to join the Premiership club from Toulon.
Seven uncapped players feature in Scotland's squad for the Six Nations, with three of those selected at hooker.
After naming his Six Nations squad, coach Warren Gatland believes a strong start could hold the key to a title-winning campaign for Wales.
Leinster have a long list of injury concerns involving Ireland internationals and Luke McGrath has now been ruled out of the Six Nations.
Ahead of the Six Nations, George Ford says he will always prioritise team success over his own battle with Owen Farrell for selection.
Leigh Halfpenny is not expected to feature in the first couple of rounds of the Six Nations, but he was named in Warren Gatland's...
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Bristol Bears have pulled off a coup by signing Nathan Hughes from Wasps, who are also losing Willie le Roux at the end of...
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Bath have confirmed number eight Taulupe Faletau broke his arm in his first match since recovering from the same injury.