Leinster delivered a fantastic performance against the Ospreys, racking up 52 points as seven different players crossed for tries.
Victory over Hong Kong in Marseille ensures Canada will maintain their record of featuring in every edition of the Rugby World Cup.
There were Premiership wins for Newcastle Falcons and Worcester Warriors on Friday, with the former moving off the foot of the table.
Adam Ashley-Cooper and Kurtley Beale will miss Australia's Test against England after breaching a "relatively minor intra-team rule".
David Pocock will not play at Twickenham on Saturday after the Wallabies flanker failed a fitness test.
As links to the All Blacks continue to linger, Ireland coach Joe Schmidt will oversee the Test against the USA before confirming his future.
Jamie George will provide England with steel early on against Australia, says coach Eddie Jones.
Jacques Brunel has made two changes to his starting XV with Benjamin Fall and Rabah Slimai returning for France.
Siya Kolisi will lead an unchanged South Africa XV against Wales as the Springboks look to finish 2018 on a high.
David Pocock has recovered from a neck injury to take his place in Australia's team to take on England.
Joe Schmidt has made 14 changes to the Ireland side that beat New Zealand for this weekend's Test against the United States.
Liam Williams starts at full-back, with Wales largely returning to the team that beat Australia against South Africa this weekend.
Dylan Hartley is set to break the record for Test appearances at Twickenham, but the co-captain will start on the bench.
Beauden Barrett, Damian McKenzie, captain Kieran Read and Ardie Savea are the only players to keep their places in the All Blacks side.
Gregor Townsend has again shaken up his Scotland team, making eight changes for the clash with Argentina.
A teenager admitted attacking Gareth Thomas last weekend and France will show their support for the Wales legend on Saturday.