Joe Schmidt has made 14 changes to the Ireland side that beat New Zealand for this weekend's Test against the United States.
Liam Williams starts at full-back, with Wales largely returning to the team that beat Australia against South Africa this weekend.
Dylan Hartley is set to break the record for Test appearances at Twickenham, but the co-captain will start on the bench.
Beauden Barrett, Damian McKenzie, captain Kieran Read and Ardie Savea are the only players to keep their places in the All Blacks side.
Gregor Townsend has again shaken up his Scotland team, making eight changes for the clash with Argentina.
A teenager admitted attacking Gareth Thomas last weekend and France will show their support for the Wales legend on Saturday.
Sam Cane broke his neck playing for New Zealand but hopes to be back in action for the Chiefs by the end of the...
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Eddie Jones thought "here we go again" when he heard David Pocock may not be feature in the Cook Cup showdown.
England will complete their 2018 programme with a clash against Australia at Twickenham.
Gareth Thomas requested that the teenager who attacked him was dealt with through restorative justice.
Bristol led Exeter by 14 points in the second half, but Rob Baxter's side snatched a dramatic victory in time added on.
Gareth Thomas claims to have been targeted for his sexuality in an attack in Cardiff.
Steve Hansen declared that Ireland are the number one team in the world and favourites for the World Cup after beating the All Blacks.
France secured their first win since March, Teddy Thomas helping himself to a double with Gael Fickou impressing on his return.
New Zealand failed to score a try in Dublin, underlining Ireland's remarkable commitment in defence as they defeated the world champions.
After Saturday's win over Italy, Michael Cheika cannot wait for Australia's clash with England at Twickenham next weekend.