Ellis Jenkins will lead Wales for the first time against South Africa on Saturday, while George North starts at centre.
Cardiff Blues forward Jenkins steps into the lead role for Warren Gatland’s side in the absence of Alun Wyn Jones, and he will head a team that includes a first cap for scrum-half Tomos Williams.
The more familiar name of North also starts, although the Ospreys-bound back will take up a different position, moving in from the wing.
“Saturday is a huge opportunity for this squad and for players individually,” Gatland told a media conference.
“Everything we are doing is geared for the Rugby World Cup in 15 months’ time and the next three matches are a hugely important part of our development.
“This weekend is an opportunity for players to build on their Test rugby experience and lay a marker down for the jersey and for the position going forward.
“I think there are exciting selections across the team and I’m looking forward to Saturday to see what we are able to do against the Springboks.”
— Welsh Rugby Union (@WelshRugbyUnion) May 31, 2018
Wales: Hallam Amos, Tom Prydie, George North, Owen Watkin, Steff Evans, Gareth Anscombe, Tomos Williams; Nicky Smith, Elliot Dee, Dillon Lewis, Bradley Davies, Cory Hill, Seb Davies, Ellis Jenkins, Ross Moriarty
Replacements: Ryan Elias, Wyn Jones, Rhodri Jones, Adam Beard, Aaron Wainwright, Aled Davies, Rhys Patchell/Gareth Davies, Hadleigh Parkes
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