Maro Itoje will be unable to aid England's bid to win the Six Nations after injury ruled him out of the Scotland game.
Having suffered defeat to Bristol last time out, Gloucester responded in emphatic fashion with a resounding away win over Harlequins.
Brett Connon held his nerve with a late penalty to give Newcastle victory at Wasps, while Exeter also did the Falcons a favour.
Saracens suffered a second defeat in three at Bath, while Sale Sharks piled on the agony for Leicester Tigers.
Kieran Read had been linked with Racing 92 and a Premiership switch, but said it was a "pretty straightforward" decision to move to Japan.
An injury to Shambeckler Vui and suspension for Tolu Latu has forced the Waratahs to bring in Tatafu Polota-Nau as short-term cover.
Newcastle Falcons closed the gap on second-bottom Worcester Warriors to five points with a 17-6 victory in the Premiership on Sunday.
Saracens eased past Northampton Saints but table-topping Exeter Chiefs had to repel a second-half rally from Sale Sharks.
Gloucester let Friday's Premiership match slip through their fingers late on at Bristol Bears.
Mark McCall hailed Schalk Burger as "one of rugby's truly great players" after the back-row decided to return to South Africa.
Mathew Tait, who made his England debut at the age of 18, has called time on his career on medical advice.
Worcester Warriors eased their relegation fears with a third victory of the season over Leicester Tigers, who have lost five in a row.
Saracens' defeat on Friday left the door ajar for Exeter Chiefs, who downed Newcastle Falcons to go top of the Premiership.
Ben Morgan's brace led Gloucester to another big victory as they fended off a fast-finishing Saracens.
Eddie Jones says only Manu Tuilagi can decide his future amid reports he is set for a big-money move to the Top 14.
Northampton Saints legend Tom Wood has extended his contract with the Premiership club.