Experienced England full-back Mike Brown will miss the rest of the Premiership season, Harlequins have confirmed.
Captain Joe Launchbury believes the future is bright for Wasps after signing a new deal.
Anthony Watson's knee injury is not as serious as first feared, but he may not play again this year.
After one appearance at the Rugby World Cup, England international Joe Cokanasiga appears set for a lengthy spell on the sidelines.
After opting not to appeal against a huge fine for breaching the salary cap, Saracens have forked out for another sanction breach.
England could be without some key players for the Six Nations due to the situation at Saracens, according to Eddie Jones.
Despite initially saying they would challenge a huge points deduction for salary cap breaches, Saracens will not launch an appeal.
Exeter Chiefs were in control at half-time, but Bristol Bears scored 20 points without reply in the second half to snatch a stunning win.
Taylor Swift proved the unlikely inspiration for beleaguered Premiership champions Saracens as they roared to victory at Gloucester.
A looming points deduction would see Saracens facing a Premiership relegation battle this season, but they defeated Gloucester on Saturday.
Rob du Preez kicked 17 points while his brother Dan scored Sale Sharks' only try in a hard-fought 28-18 Premiership victory over Wasps.
A troublesome knee injury has ended Northampton Saints and England hooker Dylan Hartley's career at the age of 33.
A fine of £5.36million fine and the deduction of 35 points will not necessitate a fire sale at Saracens, the club's chairman insists.
Having been the dominant force at home and abroad, Saracens' success is now facing significant scrutiny.
Chris Robshaw says "the pinnacle of English rugby is illegal" after Saracens were found to have breached the salary cap.
European Professional Club Rugby are not happy that Champions Cup holders Saracens were not represented at a launch event on Wednesday.