Northampton Saints claimed a win over the reigning champions at Allianz Park on the opening weekend of the Premiership season.
The fixtures for the 2019-20 Champions Cup and Challenge Cup have been revealed, with Saracens starting their title defence at Racing 92.
Brad Shields has been sent for tests on a foot injury, with Alex Dombrandt called up to the England training camp in his place.
Vereniki Goneva will remain in the Premiership after Harlequins signed the 35-year-old Fiji international.
Harlequins have welcomed former rugby league star Sean Long as an assistant coach for next season.
Harlequins have announced that former Scotland wing Tim Visser is to retire at the end of the Premiership season.
The race for the Premiership's last play-off space is hotting up and Harlequins put down their marker by beating Leicester Tigers.
Exeter Chiefs and Saracens kept winning at the top on Saturday, while Leicester Tigers' Premiership status is not yet secured.
With Ollie Devoto's try against Harlequins on Saturday, Exeter Chiefs crossed in a record 72nd consecutive Premiership match.
Morgan Parra kicked 16 points but Clermont Auvergne survived a late scare against Harlequins to progress in the European Challenge Cup.
After captaining the Reds, Australia and Harlequins, James Horwill is preparing for the final weeks of his career.
Worcester Warriors and Bristol Bears eased their relegation fears, leaving Newcastle Falcons needing a great escape to avoid the drop.
With little free-flowing rugby on show, Sale Sharks were grateful to AJ MacGinty's boot as they defeated Harlequins.
There was a tense finish at Sixways Stadium as Harlequins won by just two points over Worcester Warriors in the European Challenge Cup.
Two tries from Will Skelton helped Premiership title hopefuls Saracens fight back to beat Harlequins 27-20 at London Stadium on Saturday.
The Scarlets have signed up Wales trio Jonathan Davies, Ken Owens and Rob Evans to new deals.