Gordon Reid will make his first Scotland appearance since March as one of six changes for their clash with South Africa.
Eddie Jones has named a 30-man squad for England's remaining two November Tests, with George Kruis missing due to injury.
Wales hope to have Tomas Francis and George North fit to face Tonga, but Samson Lee has left the camp with a hamstring injury.
Warren Whiteley's calf injury could keep him out of South Africa's clash with Scotland, but Eben Etzebeth may return.
Conor Murray and Robbie Henshaw will not face the All Blacks this weekend or the United States.
Gary Graham was called up to the England Six Nations squad this year, but is set to win his first international cap for Scotland.
Mbongeni Mbonambi's try right at the end consigned France to defeat after they led South Africa by 14 points in Paris.
Sean O'Brien suffered another injury blow on Saturday, but Ireland coach Joe Schmidt says he has the resilience to make a quick return.
Wallabies and Waratahs back-rower Jack Dempsey re-signed until at least 2020.
Kieran Marmion should be fit to feature in Ireland's upcoming match against New Zealand, but Sean O'Brien will play no part.
South Africa rallied from a 14-point deficit in the second half to secure a thrilling Test victory over France in Paris.
Kieran Marmion, Bundee Aki and Luke McGrath crossed to give Ireland a largely unconvincing win over Argentina.
Having played the last time Wales beat Australia 10 years ago, Alun Wyn Jones was left feeling old after Saturday's win over the Wallabies.
For the first time since November 2008, Wales were able to celebrate victory over Australia after a tense affair in Cardiff.
New Zealand edged England in an enthralling Test on Saturday, but Owen Farrell is more concerned about beating them at the World Cup.
Sam Underhill thought he had crossed for a winning England score against New Zealand, but Courtney Lawes was deemed offside.