Schalk Brits has not played for the Springboks since 2015, but the veteran hooker is set to come off the bench against England.
George Ford has been dropped for the third Test against South Africa, with Danny Cipriani finally getting his chance from the start.
Morgan Parra will lead Les Bleus against the All Blacks when they attempt to avoid a whitewash, with Mathieu Bastareaud rested.
Joe Schmidt has made five alterations to his starting line-up, while Lukhan Tui and Nick Phipps come into the Australia side in Sydney.
After naming the same side for the first two Tests, Steve Hansen has opted to make changes for the game in Dunedin.
Eddie Jones is under pressure after a dire run of England's results, but he sees significant success on the horizon.
Ireland have not ruled out international recalls for Paddy Jackson and Stuart Olding.
Despite suffering a nasty cheekbone injury in Melbourne, Adam Coleman expects to play in Australia's series decider with Ireland.
England have lost five consecutive Tests but Eddie Jones thinks they can learn from the "hard lessons" they are being given.
With Will Genia undergoing surgery on a broken arm, Australia have added Waratahs scrum-half Jake Gordon to their squad.
Beauden Barrett will not be risked for the third Test against France, but Ricky Riccitelli and Jackson Hemopo could win their first caps.
Argentina are on the look-out for a new coach ahead of next Saturday's meeting with Scotland, after Daniel Hourcade resigned.
South Africa made a slow start against England but, to Rassie Erasmus' delight, came roaring back to clinch the series.
England let a 12-0 lead slip to lose to South Africa on Saturday, leading captain Owen Farrell to conclude that his side lack composure.
Scotland became the first tier-one nation to be defeated by USA after a 30-29 loss in Houston on Saturday.
It was not a comeback on the same scale as the first Test, but South Africa fought back from 12-0 down to beat England...
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