Munster top Pro14 Conference B after their 28-12 victory over Ospreys, while Cardiff Blues were defeated 23-14 by Ulster.
Friday's Pro14 fixtures saw a trio of easy victories as the Cheetahs, Leinster and Connacht all won by big margins.
Ulster suffered a hammering in Bloemfontein, where wing Anthony Volmink scored three of nine tries for the Cheetahs.
Stephen Larkham has agreed to a new challenge with Irish province Munster, signing a deal until June 2022.
Munster gave it a great go, but Leinster have the chance to be crowned Pro14 champions once again.
After Billy Vunipola was confronted by a fan in a Munster shirt on Saturday, the Irish province distanced themselves from the supporter.
After the controversy surrounding his support for Israel Folau, Billy Vunipola declared himself "grateful" to be playing for Saracens.
Michael Rhodes and Billy Vunipola scored tries but Owen Farrell's 22 points from the tee were key for Saracens against Munster.
Leinster will be led by the fit-again Johnny Sexton when they take on Toulouse in Sunday's European Champions Cup semi-final.
Munster are not optimistic over their chances of being able to count on Joey Carbery against Saracens in the Champions Cup on Saturday.
Edinburgh's Pro14 play-off hopes hang by a thread after a damaging home defeat to Ulster, who extended their own domestic season.
Munster have secured the future of head coach Johann van Graan until 2022. The South African signed a new deal on Monday.
The top two teams in Conference A in the Pro14 were in fine form on Friday as they enjoyed comprehensive victories.
Owen Farrell missed Saracens' Champions Cup win over Glasgow Warriors as his wife went into labour before kick-off.
Ireland's deputy fly-half Joey Carbery has been rewarded for an impressive first season at Thomond Park with an extended deal.
Bonus-point wins for Glasgow Warriors and Munster mean the top two in Conference A remain three points apart.