Initially ruled out of the Wales Six Nations game for "medical reasons", England confirmed Mako Vunipola is in self-isolation.
England will not have Mako Vunipola back to face Wales, with the prop ruled out for the Six Nations encounter at Twickenham.
Ireland's clash with Italy in Dublin is the only Six Nations match to be postponed due to the coronavirus.
Nemani Nadolo will be in Leicester Tigers colours next season after the Premiership club lured the former Fiji powerhouse from Montpellier.
England prop Mako Vunipola features in their 34-man squad ahead of the game with Wales, with Jack Maunder called up.
Chris Ashton is on the market after Premiership contenders Sale Sharks reached an agreement with the wing to terminate his contract early.
Fly-half Finn Russell will play no part in the Six Nations, but could make his Scotland return later this year.
Ben Botica scored two second-half penalties to help Bordeaux Begles to a 26-24 victory in a tightly contested match against Castres.
Racing 92, Clermont Auvergne, Bayonne, Pau and Brive earned victories in Top 14, with leaders Bordeaux-Begles not in action.
Munster and Dragons earned home Pro14 victories over Scarlets and Cheetahs respectively.
There were wins for Harlequins, Saracens and Leicester on a dramatic day of Premiership action.
The Stormers and the Bulls suffered disappointing home defeats in Super Rugby, with the Blues and the Jaguares emerging triumphant.
After three consecutive defeats to start the Super Rugby season, the Waratahs finally got off the mark on Friday.
The IRFU has confirmed the postponement of Ireland versus Italy in the interest of public health.
Absent for the opening three matches of the Six Nations, Anthony Watson is back in the mix for England this week.
Cian Healy will miss the remainder of the Six Nations after the prop was injured during Ireland's loss to England.