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Wasps won for only the second time since September with a fit-again Joe Launchbury back in the side.
Having suffered their first Premiership defeat of the season in their last away game, the Exeter Chiefs lost again at Northampton Saints.
Cobus Reinach and Luther Burrell scored intercept tries and Dan Biggar had a good outing at the tee in a comfortable win for Northampton.
Timisoara Saracens have been punished for not doing enough to try to get the game against Northampton Saints to go ahead last Saturday.
There were wins for the Ospreys, Sale Sharks and Clermont Auvergne in the European Challenge Cup on Saturday.
Defending champions Saracens have won each of their opening nine Premiership fixtures as they stayed perfect by beating Wasps 29-6.
There were wins in the Premiership on Saturday for Exeter, Sale and Wasps, the latter triumphing despite a stunning Bristol fightback.
Teenage lock Joel Kpoku came off the bench to give Saracens a seventh Premiership wins out of seven, which put them back at the summit.
Sara Cox will take charge as Wasps face Northampton Saints, becoming the first female referee in the Premiership Rugby Cup.
Having been beaten 82-21 by La Rochelle six days earlier, Enisei were once again outplayed by the French club.
Courtney Lawes had been linked with a move to the Top 14, but the long-serving lock will be staying at Franklin's Gardens.
Saracens and Exeter Chiefs met in last term's Premiership final and they are making the early running once more this season.
Northampton Saints slumped to a third defeat in four as Bath won at The Rec, while Wasps and Bristol also secured victories.
Saracens needed two late tries from David Strettle to secure a come-from-behind victory over Northampton Saints.
Dan Biggar kicked 17 points and Dylan Hartley came off the bench to score a try as Northampton Saints edged out Harlequins.
Danny Cipriani produced a sensational pass for Charlie Sharples' try while Billy Twelvetrees kicked 17 points in Gloucester's victory.
