Wales' match with Ireland could make or break England's Six Nations campaign and Eddie Jones says the leaders are tiring.
Sean O'Brien, Tadhg Beirne and Rob Kearney come in for Ireland as Joe Schmidt makes three changes against Wales.
England have made four changes for their Six Nations clash with Scotland, with Joe Cokanasiga surprisingly omitted from the squad.
Conor O'Shea has handed Marco Zanon his Italy debut as one of five changes for their Six Nations clash with France.
Scotland's hopes of retaining the Calcutta Cup have been boosted by the return of Sam Skinner for Saturday's clash with England.
Warren Gatland has gone with a tried and trusted starting XV as Wales chase Grand Slam glory against Ireland in the Six Nations.
Wesley Fofana will start in his final Six Nations match as France travel to Italy looking for their second win of the 2019 tournament.
Wales, England and Ireland all head into the final weekend of the Six Nations season with a chance to secure the title.
Former captain Sam Warburton has praised Warren Gatland for turning Wales into a world force during his near 12 years in charge.
Saracens scrum-half Ben Spencer has been added to England's squad after Dan Robson was ruled out due to illness.
Flanker Josh van der Flier will play no part in Ireland's attempt to deny Wales a Grand Slam this weekend.
Ireland superstar Johnny Sexton has pointed to recent big results against New Zealand and England as evidence that they can defeat Wales.
Mark Keohane’s Independent Media Rants and Raves following a weekend of Super Rugby, Sevens and Six Nations. TOP RAVE: Handre Pollard remains South Africa’s...
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Tommy Seymour, Blair Kinghorn and Stuart Hogg will miss Scotland's final Six Nations match, while France will also be without two players.
Maro Itoje will be unable to aid England's bid to win the Six Nations after injury ruled him out of the Scotland game.
Ireland's bonus-point win over France was Joe Schmidt's final home Six Nations game at the helm and he was feeling emotional afterwards.