Japan recovered from a rough start on Friday to begin their home Rugby World Cup campaign with victory over Russia in Tokyo.
Toulon and Agen each won in the Top 14 on Sunday, with Racing 92 unable to complete a turnaround while Montpellier were outplayed.
The top two in the Top 14 claimed huge victories to stay unbeaten as both the defending champions and last year's runners-up were beaten.
Clermont Auvergne suffered a derby defeat to Top 14 new boys Brive as defending champions Toulouse earned their first win of the season.
The top two in the Top 14 both triumphed on Saturday, with Bordeaux-Begles and Lyon improving to three wins from three this season.
The Lions almost repeated August's Currie Cup fightback against the Cheetahs in Saturday's final, falling short as their opponents held on.
Wales avoided a repeat of 2015's pre-Rugby World Cup injury problems as Ireland won 19-10 in Dublin on Saturday to take the No.1 ranking.
Michael Cheika's Wallabies head into the Rugby World Cup with no new injury concerns after getting through unscathed against Samoa.
The All Blacks fell just short of 100 points in a merciless display in Hamilton, where New Zealand scored 14 tries on Saturday.
Captain Owen Farrell converted all four of England's tries and also kicked three penalties as his side eased past Italy on Friday.
Gregor Townsend may count the cost of injuries from Scotland's final Rugby World Cup warm-up victory over Georgia.
Japan were unable to repeat their shock 2015 Rugby World Cup success over South Africa, largely due to Makazole Mapimpi's hat-trick.
Toulouse won the Top 14 last season but they have been beaten in each of their first two matches at the start of the...
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The second round of Top 14 fixtures saw hard-fought wins for Clermont Auvergne, La Rochelle and Montpellier, among others, on Saturday.
Scotland earned their first away Test win for 14 months against Georgia, with Rory Hutchinson impressing on his full debut.
Jacob Stockdale scored twice as Ireland improved to beat Wales in a hard-fought affair in Cardiff on Saturday, ahead of the Rugby World Cup.