France have made two changes to their starting line-up against Argentina, with Yoann Huget selected for the first time in a year.
Jordan Petaia will become Australia's youngest debutant for a decade in a much-changed side in Padova.
Full-back Rob Kearney and centre Garry Ringrose have recovered from injuries in time to start against New Zealand.
Joe Cokanasiga comes into the side as Eddie Jones makes 11 changes to the England team that started against New Zealand.
Steve Hansen has made just one enforced change for the All Blacks' showdown with Ireland, Ryan Crotty coming in for Sonny Bill Williams.
England's defence coach John Mitchell believes centre Manu Tuilagi has a chance to play against Australia later this month.
Gordon Reid will make his first Scotland appearance since March as one of six changes for their clash with South Africa.
Bath have been boosted by the news of new contracts for four players, including England star Anthony Watson.
Eddie Jones has named a 30-man squad for England's remaining two November Tests, with George Kruis missing due to injury.
Wales hope to have Tomas Francis and George North fit to face Tonga, but Samson Lee has left the camp with a hamstring injury.
Warren Whiteley's calf injury could keep him out of South Africa's clash with Scotland, but Eben Etzebeth may return.
Conor Murray and Robbie Henshaw will not face the All Blacks this weekend or the United States.
Gary Graham was called up to the England Six Nations squad this year, but is set to win his first international cap for Scotland.
Mbongeni Mbonambi's try right at the end consigned France to defeat after they led South Africa by 14 points in Paris.
Sean O'Brien suffered another injury blow on Saturday, but Ireland coach Joe Schmidt says he has the resilience to make a quick return.
Stuart Hogg said the time has come to challenge himself in a different environment after nine seasons with Glasgow Warriors.