Jordan Larmour grasped his first opportunity to start for Ireland with both hands, scoring three tries and laying on another in Chicago.
There were wins for Connacht and Ulster in Saturday's Pro14 action.
Eben Etzebeth suffered what appeared to be an ankle injury early in the second half of the Springboks' defeat against England.
South Africa dominated England in the second half, but Eddie Jones was pleased with the way his side hung in there and fought back.
South Africa paid the price for letting England off the hook at Twickenham, where Eddie Jones' men gained revenge for a series loss in...
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Wales started their November internationals with victory over Scotland, Jonathan Davies scoring on his return from a long injury lay-off.
Kieran Read wants to keep playing after the World Cup, which will likely mark the end of the All Blacks captain's international career.
Jordie Barrett made another mistake in the All Blacks' win over Japan, but Steve Hansen came to his defence.
There was no shortage of action in Tokyo as New Zealand beat Japan 69-31 in a contest featuring 15 tries.
Glasgow Warriors stretched their lead at the top of Conference A to nine points thanks to Nikola Matawalu's hat-trick against Ospreys.
Beauden Barrett will make history if he is named the best player in the world again, but he has some strong competition.
Manu Tuilagi has suffered yet another injury blow, a groin problem ruling him out of the showdown with South Africa.
Both Ireland and Italy are lacking several key men for this weekend's Test meeting in the United States.
Australia will be determined to end their tour with a morale-boosting win over England after a barren run against their rivals.
Injuries have ravaged England's forward pack, but Eddie Jones is excited and confident heading into the South Africa Test.
Rassie Erasmus has made seven changes to his South Africa side, bringing in Ivan van Zyl as well as regulars including Warren Whiteley.