A club-record crowd of 30,174 witnessed Newcastle Falcons win at St James' Park as Toby Flood kicked 20 points against Northampton.
Despite Filipo Daugunu's stunning solo try, the Reds saw their comeback bid fall short as the Stormers triumphed in Cape Town.
Super Rugby's last unbeaten run has been broken after the Hurricanes got the better of the Highlanders.
There were wins for Glasgow Warriors, Edinburgh and Cheetahs in Pro14 on Saturday, with Duncan Weir among the star performers.
Exeter Chiefs moved 11 points clear at the top of the Premiership after a dramatic victory over Bath at the Recreation Ground.
Newcastle Falcons are unlikely top-four contenders in the Premiership and Toby Flood said they can play with a smile on their faces.
Ireland's record-breaking winger Jacob Stockdale has been named as the Six Nations Player of the Championship.
After successive losses, the Crusaders rediscovered that winning feeling with a 33-14 victory over the Bulls in Super Rugby on Friday.
As coaching changes continue at London Irish, director of rugby Nick Kennedy has left the club.
RFU boss Steve Brown accepts England's Six Nations display was "very disappointing", but says he will be sticking with Eddie Jones.
Toby Flood thinks Eddie Jones should have managed the workload of the England players more efficiently in training during the Six Nations.
Former All Black Dylan Mika has died suddenly at the age of 45, his family have announced.
Heyneke Meyer has returned to coaching, taking the role at Stade Francais as the Top 14 club look to stave off relegation.
Iain Henderson has put pen to paper on a new deal with the Irish Rugby Football Union until June 2021.
Ireland captain Rory Best will lead them into the 2019 World Cup after extending his contract.
Wales wing George North missed a Northampton training session this month and has been punished by the Premiership club.