South Africa were beaten in bizarre circumstances by Wales on Saturday, with new coach Rassie Erasmus acknowledging the need to improve.
There was a late twist in the tale as Rassie Erasmus suffered defeat to Wales in his first match as South Africa coach.
Ireland are already looking towards defending their Six Nations title and attacking the World Cup, according to coach Joe Schmidt.
Wales coach Warren Gatland has named Ellis Jenkins as captain for his side's clash with South Africa on Saturday.
Australia full-back Reece Hodge knows Six Nations champions Ireland possess quality across their backline that can worry the Wallabies.
Seven uncapped players will be given the chance to impress Rassie Erasmus when South Africa face Wales in Washington on Saturday.
Dylan Hartley is "feeling a lot better" and is looking forward to resuming his career for club and country.
History will be made when Stormers flanker Siya Kolisi leads the Springboks in three home Tests against England in June.
Toulouse's Richie Gray has joined Alex Dunbar in pulling out of the Scotland squad for their June fixtures.
Jared Payne has ended his playing career on medical advice and will take up a role as defence coach at Ulster.
Wales will have to do without Aaron Shingler and Ashton Hewitt when they come up against the Springboks and the Pumas in June.
World Rugby's proposed new law to protect players in the tackle has been endorsed by All Blacks coach Steve Hansen.
A mammoth 43-man squad has been selected for matches against Wales and England by Springboks chief Rassie Erasmus.
Saracens finished their Premiership final win over Exeter Chiefs without Owen Farrell, but his injury was not serious.
England have named four uncapped players in their starting XV to face the Baa Baas, while Danny Cipriani is among the replacements.
Teddy Thomas is back in the fold for France, but captain Guilhem Guirado will sit out the tour of New Zealand next month.